Researchers in Sweden and the United States have achieved a historic medical breakthrough by performing the first-ever transplant of gene-edited insulin-producing cells in a human.
A 42-year-old man with type 1 diabetes received nearly 80 million CRISPR-Cas12b modified cells implanted in his forearm. These cells were designed to evade the immune system and produce insulin naturally.
đź“Š Results after 12 weeks:
Cells continued to produce insulin without immunosuppressive drugs.
Patient’s HbA1c levels dropped by 42%, showing improved blood sugar control.
Insulin release was observed after meals, although additional insulin was still required due to the limited initial cell dose.
🔬 What’s Next?
The trial only involved one patient, who will be monitored for a year. If results remain successful, future trials may test higher doses, potentially revolutionizing treatment for millions living with type 1 diabetes worldwide.
